第二报:几种不同炮制方法对草烏主成分的影响。作者試驗了几种不同的炮制方法,結果表明:草烏經加水处理,其麻辣程度与生物碱含量及毒性,随着水漂时間的加长而逐漸减少。水漂液的PH值在4.0～6.0之間,其酸度随着換水次数的增多而下降。每日換水,可溶出一部分生物碱,因此认为,浸漂确能起到一定的减毒作用,并与浸漂溫度、生药不同部位、加水量的多少和換水次数等有关。其次就加热处理方法进行研究,結果认为烏头碱經加热后分解,确能减少原来毒性,但生药本身受热不均,且时間及溫度等也不易掌握。古时由火炮法逐漸改为水炮法,其原因可能在此。水火共同处理的方法比单純用水或火处理方法为完全,因經加水加热处理更易于促进烏头碱的 Second report: The effect of several different processing methods on the main components of Aconitum. The authors experimented with several different methods of processing. The results showed that the degree of malaizing and alkaloids content and toxicity of grass and worms increased gradually as water drift time increased. The pH of the water-displaced liquid is between 4.0 and 6.0, and its acidity decreases with the number of water changes. Daily change of water, soluble part of the alkaloids, so that the dip float can indeed play a role in reducing toxicity, and the dip drift temperature, different parts of crude drugs, how much the amount of water and the number of water changes and so on. Secondly, the heat treatment method was studied. As a result, aconitine was decomposed after heating, and the original toxicity could be reduced. However, the crude drug itself was unevenly heated, and the time and temperature were not easily grasped. In ancient times, the artillery method was gradually changed to the water gun method. The reason may be this. The method of joint treatment of water and fire is more complete than that of water or fire alone, because it is easier to promote the use of aconitine by heating with water.