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目的分析新生儿缺氧缺血性脑病的临床特点,提高对该病的认识。方法回顾性分析2003年1月至2006年6月入住本院的56例新生儿缺氧缺血性脑病患儿临床资料。结果本院缺氧缺血性脑病患儿以足月正常体重者为主,多数有围生期窒息并伴有各种围生期高危因素,大多数有宫内窘迫表现,多数患儿合并有呼吸等系统的疾病,临床表现为抽搐、兴奋、激惹等神经系统症状,头颅CT示脑缺氧、脑水肿、基底核丘脑损伤为主的脑损伤,多数病例经治疗治愈或好转出院。结论足月儿有窒息、围生期高危因素、宫内窘迫者需高度警惕缺氧缺血性脑病的可能,应结合临床及头颅CT综合考虑作出诊断。
Objective To analyze the clinical features of neonatal hypoxic-ischemic encephalopathy and to improve its understanding of the disease. Methods The clinical data of 56 neonates with hypoxic-ischemic encephalopathy admitted to our hospital from January 2003 to June 2006 were retrospectively analyzed. Results Hypoxic ischemic encephalopathy in our hospital, with full-term normal weight, most of the perinatal asphyxia accompanied by a variety of perinatal risk factors, the majority of intrauterine distress performance, the majority of children with a combination of Respiratory system diseases, clinical manifestations of convulsions, excitement, irritation and other neurological symptoms, head CT showed cerebral hypoxia, cerebral edema, basal ganglia brain damage injury-based brain injury, the majority of cases cured or improved after treatment was discharged. Conclusion The full-term infants with asphyxia, perinatal risk factors, intrauterine distress should be highly alert to the possibility of hypoxic-ischemic encephalopathy should be combined with clinical and cranial CT to make a diagnosis.