论文部分内容阅读
目的观察重度妊娠高血压疾病(HCDP)对早产儿血液系统的影响。方法回顾性分析北京大学第一医院新生儿重症监护室2008年1月至2011年6月收治的先兆子痫和子痫母亲之早产儿75例(观察组),以同期收治的健康母亲之早产儿60例作为对照组,比较两组的血常规特点、变化及影响因素,以及早产儿常见相关并发症的差异。结果观察组出生体重和胎龄小于对照组,小于胎龄儿(SGA)较对照组多(P<0.01)。观察组生后6h内、2～3d及5～7d白细胞计数(WBC)、中性粒细胞绝对计数(ANC)及血小板计数(BPC)均低于对照组(P<0.01),其中WBC及ANC减少以生后6h内最多见(42.7%),BPC减少以生后2～3d最多见(49.3%)。BPC减少与患儿性别及母亲BPC状态无关(P>0.05),而与低出生体重和SGA有关(P<0.01)。观察组感染率高于对照组(P<0.01),其他常见相关并发症两组间差异无统计学意义(P<0.01)。结论重度HCDP可引起早产儿生后BPC减少和ANC减少,与低出生体重和SGA有关,临床易发生感染。
Objective To observe the effect of severe pregnancy-induced hypertension (HCDP) on the blood system of premature infants. Methods A retrospective analysis of 75 preterm infants with preeclampsia and eclampsia in the Neonatal Intensive Care Unit of Peking University First Hospital from January 2008 to June 2011 (observation group), preterm infants Sixty cases served as the control group, and the blood routine characteristics, changes and influential factors of the two groups were compared, and the common complication of premature infants was compared. Results The birth weight and gestational age in the observation group were smaller than those in the control group and were smaller than those in the control group (P <0.01). WBC, absolute neutrophil count (ANC) and platelet count (BPC) in observation group were lower than those in control group (P <0.01) within 2h, Reduced to see the most within 6h (42.7%), BPC decreased to 2 to 3d after birth, the most common (49.3%). The decrease of BPC was not related to the gender and the status of BPC (P> 0.05), but was associated with low birth weight and SGA (P <0.01). The infection rate in the observation group was higher than that in the control group (P <0.01). There was no significant difference in other common complications between the two groups (P <0.01). Conclusions Severe HCDP can cause a decrease of BPC and ANC in preterm infants, which is related to low birth weight and SGA.