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[目的]探讨影响老年直肠癌患者预后的危险因素,为改善老年直肠癌患者预后提供参考依据。[方法]选择2007年1月—2012年1月我院收治的124例老年直肠癌患者作为研究对象,通过SPSS 17.0软件分析患者生存率及预后影响因素。[结果]124例患者1年、3年、5年生存率分别为91.13%、54.03%、23.39%,中位生存时间为41个月;Ⅰ期+Ⅱ期患者3年生存率最高,为85.71%,复发患者3年生存率最低,为11.54%;COX回归分析结果显示,TNM分期、远处转移、复发、分化程度对患者预后有显著影响(P<0.05)。[结论]TNM分期、远处转移、分化程度、复发是老年直肠癌患者独立危险因素,可作为患者预后重要评估指标。
[Objective] To explore the risk factors influencing the prognosis of elderly patients with rectal cancer and provide reference for improving the prognosis of elderly patients with rectal cancer. [Methods] A total of 124 elderly patients with rectal cancer who were treated in our hospital from January 2007 to January 2012 were selected as the study subjects. SPSS 17.0 software was used to analyze the patients’ survival rate and prognostic factors. [Results] The 1-year, 3-year and 5-year survival rates of 124 patients were 91.13%, 54.03% and 23.39%, respectively. The median survival time was 41 months. The highest 3-year survival rate was 85.71 %. The lowest 3-year survival rate was 11.54% in patients with recurrent disease. The results of COX regression analysis showed that TNM stage, distant metastasis, recurrence and differentiation had a significant effect on the prognosis of patients (P <0.05). [Conclusion] TNM staging, distant metastasis, degree of differentiation and relapse are independent risk factors for elderly patients with rectal cancer and may be used as important prognostic indicators in patients.