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目的观察胸腔镜配合尿激酶胸腔内注射治疗结核性包裹性胸腔积液的效果。方法选取结核性包裹性胸腔积液患者60例,按照治疗方式的不同分为观察组和对照组各30例。观察组给予胸腔镜配合尿激酶胸腔内注射治疗,对照组给予胸腔穿刺术配合尿激酶注入治疗,比较2组患者治疗后胸膜厚度、肺功能及并发症发生率。结果观察组胸膜厚度、FEV1、FVC等指标均优于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率为3.33%,低于对照组的16.67%,差异有统计学意义(P<0.05)。结论胸腔镜配合尿激酶胸腔内注射治疗结核性包裹性胸腔积液效果满意,能较大程度改善肺功能,防止胸膜肥厚。
Objective To observe the effect of thoracoscope combined with intrapleural injection of urokinase in the treatment of tuberculous pleural effusion. Methods Sixty patients with tuberculous pleural effusion were selected and divided into observation group and control group according to the different treatment methods. The observation group was treated by thoracoscope with intrapleural injection of urokinase and the control group by thoracentesis combined with urokinase injection. The pleural thickness, pulmonary function and complication rate were compared between the two groups. Results The pleural thickness, FEV1, FVC and other indexes in the observation group were better than those in the control group, with significant difference (P <0.05). The complication rate in observation group was 3.33%, which was lower than that in control group (16.67%), the difference was statistically significant (P <0.05). Conclusions Thoracoscopy combined with intrapleural injection of urokinase for tuberculous pleural effusion is satisfactory, which can greatly improve lung function and prevent pleural hypertrophy.