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目的:探讨戒烟门诊药物治疗+专业心理、行为干预的戒烟效果。方法:将2010年1月到2010年6月收治的戒烟患者109例分为普通门诊组58倒、戒烟门诊组51例。均给予伐尼克兰治疗期3个月,普通门诊组只在首次就诊时进行3 min的烟草危害知识宣教,戒烟门诊组每次随访时进行20~30 min面对面的心理及行为的干预。结果:戒烟门诊组受试者9~12周、9~18周及9~24周持续戒断率明显高于普通门诊组(P<0.05)。戒烟门诊组受试者9、12、18、24周时点戒断率明显高于普通门诊组(P<0.05)。戒烟门诊组受试者在12、18、24周复吸率明显低于普通门诊组(P<0.05)。戒烟门诊组受试者出现焦虑、烦躁、易激惹和体质量增加的人数明显少于普通门诊组(P<0.05)。结论:戒烟药物伐尼克兰具有较好的有效性和安全性,药物治疗+专业心理、行为干预是一种行之有效、可行性强的戒烟模式。
Objective: To explore smoking cessation drug treatment + professional psychology, behavioral interventions to stop smoking. Methods: From January 2010 to June 2010, 109 cases of smoking cessation were divided into general outpatient group 58 down, smoking cessation group 51 cases. Were treated with varenicline for 3 months. The general outpatient group only carried out a 3-minute training in tobacco hazard knowledge at the first visit. The face-to-face psychological and behavioral interventions were performed at smoking cessation outpatient clinics for 20-30 minutes at each follow-up visit. Results: Cessation abstinence rate of smoking cessation group was significantly higher than that of general outpatient group (P <0.05) at 9-12 weeks, 9-18 weeks and 9-24 weeks. At the quit smoking outpatient group, the abstinence rate at 9, 12, 18 and 24 weeks was significantly higher than that of the general outpatient group (P <0.05). The rate of relapse was significantly lower in the smoking cessation clinic group at 12, 18 and 24 weeks than that in the general outpatient group (P <0.05). The number of anxiety, irritability, irritability and weight gain in the smoking cessation clinic group was significantly less than that in the general outpatient group (P <0.05). Conclusion: Smoking cessation varenicline has good efficacy and safety. Medication + professional psychology and behavioral intervention are an effective and feasible smoking cessation model.