本文综述滤过除菌的条件、滤过系统和滤材的选择、控制以及滤过除菌法的应用。一、简介十九世纪中叶,人们认识了微生物的危害后,逐渐产生了滤过除菌法,并发明和使用了瓷滤器、硅藻土滤器、膜滤器、石棉板(或纤维板)滤器、滤盘、滤简、垂熔玻璃滤器等。上述滤器各有利弊,如:瓷滤器主要的缺点是需要较高的滤过压(40～50标准大气压表压);石棉纤维滤器具有吸附作用,故用于胰岛素、血浆等天然产品除去热原,其缺点是掉絮;滤筒可反复使用,但净化过程及确定滤筒完整 This article summarizes the conditions of filtration sterilization, filtration system and filter selection, control and application of filtration sterilization. I. INTRODUCTION In the mid-nineteenth century, people became aware of the dangers of microorganisms and gradually developed the process of filtration and sterilization. They also invented and used porcelain filters, diatomite filters, membrane filters, asbestos board (or fibreboard) filters, Plate, filter Jane, glass frit and other filters. The above filters have their own advantages and disadvantages, such as: porcelain filter the main disadvantage is the need for higher filtration pressure (40 ~ 50 standard atmospheric gauge pressure); asbestos fiber filter with adsorption, it is used for insulin, plasma and other natural products to remove pyrogen , The disadvantage is off flocculation; cartridge can be used repeatedly, but the purification process and determine the cartridge integrity