丁丙诺啡(buprenorphine)是一种中枢神经系统激动-拮抗混合型阿片类麻醉剂。本文报告了5例因硬膜外给药出现幻觉症状。病例1,女,40岁,在全麻下行4～5腰椎后侧融合术。经硬膜外插管给丁丙诺啡150μg,每8～12h1次,总剂量为900μg。术后48h,患者诉说做恶梦,常因室内有幻影而悲伤、忧虑。一旦停 Buprenorphine is a central nervous system agonist-antagonist mixed opioid. This article reports 5 cases of hallucinations due to epidural administration. Case 1, female, 40 years old, under general anesthesia 4 ~ 5 lumbar fusion. The epidural catheter to buprenorphine 150μg, every 8 ~ 12h1 times, the total dose of 900μg. 48h after surgery, the patient complained of nightmares, often because of indoor phantom and sadness, anxiety. Once stopped