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本文研究了胸腺素对实验性精索静脉曲张鼠催乳素(PRL)分泌的影响.用放射免疫法测定了血清和睾丸组织中PRL的水平.发现实验性精索静脉曲张未用药组左侧睾丸组织中的PRL水平与假手术组比较明显升高(P<0.01),同组两侧比较有显著性差异(P<0.01).给予胸腺素4周后,两侧睾丸组织中的PRL水平明显降低,尤其以左侧睾丸组织较为显著(P<0. 01).提示PRL水平异常是精索静脉曲张不育的原因之一.胸腺素参与PRL的分泌和功能的调节,对实验性精索静脉曲张鼠生殖内分泌功能的调控具有重要的影响.
In this paper, we studied the effect of thymosin on the secretion of prolactin (PRL) in experimental varicocele rats.We measured the levels of PRL in serum and testis by radioimmunoassay and found that the left testes The level of PRL in the testis tissue was significantly higher than that in the sham operation group (P <0.01), and there was a significant difference between the two sides of the same group (P <0.01) (P <0.01), suggesting that the abnormal PRL level is one of the causes of varicocele infertility.Thymosin is involved in the regulation of PRL secretion and function, the experimental spermatic cord The regulation of reproductive and endocrine function of varicose veins has an important impact.