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AIM To assess the role of thyroid disease as a risk forfractures in Crohn’s patients.METHODS:A cross-sectional study was conducted from1998 to 2000.The study group consisted of 210 patientswith Crohn’s disease.A group of 206 patients withoutinflammatory bowel disease served as controls.Primaryoutcome was thyroid disorder.Secondary outcomes includeduse of steroids,immunosuppressive medications,surgeryand incidence of fracture.RESULTS:The prevalence of hyperthyroidism was similarin both groups.However,the prevalence of hypothyroidismwas lower in Crohn’s patients(3.8 % vs 8.2 %,P=0.05).Within the Crohn’s group,the use of immunosuppressiveagents(0 % vs11%),steroid usage(12.5 % vs37 %),smallbowel surgery(12.5 % vs 28 %)and large bowel surgery(12.5 % vs27 %)were lower in the hypothyroid subset ascompared to the euthyroid subset.Seven(3.4 %)Crohn’spatients suffered fracture,all of whom were euthyroid.CONCLUSION:Thyroid disorder was not found to beassociated with Crohn’s disease and was not found toincrease the risk for fractures.Therefore,screening forthyroid disease is not a necessary component in themanagement of Crohn’s disease.
AIM To assess the role of thyroid disease as a risk for fractures in Crohn’s patients. METHODS: A cross-sectional study was conducted from 1998 to 2000. The study consisted of 210 patients with Crohn’s disease. A group of 206 patients without inflammatory bowel disease served as controls Secondary prevalence of hypothyroidism was lower in Crohn’s patients (3.8% vs 8.2%, P = 0.05) .Within the Crohn’s group, the use of immunosuppressive agents (0% vs11%), steroid usage (12.5% vs37%), smallbowel surgery (12.5% vs28%) and large bowel surgery the hypothyroid subset ascompared to the euthyroid subset. Seven (3.4%) Crohn’spatients suffered fracture, all of whom were euthyroid. CONCLUSION: Thyroid disorder was not found to beassociated with Crohn’s disease and was not fo und toincrease the risk for fractures.Therefore, screening forthyroid disease is not a necessary component in the management of Crohn’s disease.