自六十年代以来,随着大孔离子交换树脂的问世,大孔吸附树脂也得到了很快的发展。美国罗姆哈斯公司生产的Amberlite XAD系列和日本三菱化成公司生产的Diaion HP系列吸附树脂在许多领域得到广泛的应用,特别有效地应用于发酵液中抗菌素和生物活性物质的提取(如头孢菌素的提取)和脱色。我国现在研制生产的吸附树脂大多是以二乙烯苯为交联剂的苯乙烯、丙烯酸甲酯或丙烯腈与二乙烯苯的大孔共聚物,具有较高的比表面积和孔穴率,在脱色、分离、色谱和药物提取上也取得较好的应用效果。 Since the 1960s, with the advent of macroporous ion exchange resins, macroporous adsorption resins have also been developed rapidly. Amberlite XAD series produced by the United States Rohm and Haas Company and Diaion HP series adsorption resin produced by Japan’s Mitsubishi Chemical Corporation have been widely used in many fields and are particularly effective in the extraction of antibiotics and bioactive substances in fermentation broths Prime extraction) and bleaching. Nowadays, most of the adsorptive resins developed and produced in our country are macroporous copolymers of styrene, methyl acrylate or acrylonitrile and divinylbenzene with divinylbenzene as cross-linking agent, which have high specific surface area and porosity, Separation, chromatography and drug extraction also achieved good results.