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卵巢卵泡膜增殖综合症在1949年首先为Guliner及Shippel所描述。临床上表现男性化现象,卵巢的特殊病理变化是在卵巢皮质间质中有一周围的卵泡膜细胞增生。这类疾病原来是包括在多囊卵巢综合症内的,但近年来由于类固醇测定方法的进展有利于对这疾患的准确诊断及克罗米芬的应用(此药在多囊卵巢综合症病人中能引起排卵,排卵率75%)。但对卵泡膜增殖综合症却无效。有必要将它与多囊卵巢综合症区分开来。本文报道1病例,年24岁,继发闭经6年。初潮13岁,一向月经稀少4—18月/次,肥胖,重225磅,高5.3尺,血压150/80毫米汞柱,在面颊部,下巴及颈部都有多毛;经妇科检查,阴蒂肥大,长
Ovarian follicular proliferative syndrome was first described by Guliner and Shippel in 1949. Clinical manifestations of the phenomenon of masculine ovarian special pathological changes in the ovarian cortex in a surrounding interstitial cell population of theca cell hyperplasia. Such diseases were originally included in polycystic ovary syndrome, but in recent years due to the progress of steroid determination method is conducive to the accurate diagnosis of this disease and the use of clomiphene citrate (this medicine can cause in patients with polycystic ovary syndrome Ovulation, ovulation rate of 75%). But the follicular proliferative syndrome is invalid. It is necessary to distinguish it from polycystic ovary syndrome. This article reports a case, a 24-year-old, secondary amenorrhea for 6 years. Menarche is 13 years old and has been sparsely menstruating for 4-18 months / time. It is obese, weighs 225 pounds, weighs 5.3 feet and has a blood pressure of 150/80 mm Hg. It has hirsutism in cheeks, chin and neck. After gynecological examinations, clitoral hypertrophy ,long