论文部分内容阅读
目的：研究印防己毒素对安定抑制刺激下丘脑诱发的升压反应的影响。方法：家兔用氨基甲酸乙酯和氯醛糖混合静脉麻醉，三碘季铵酚制动，人工呼吸，静脉注射安定，侧脑室注射氟安定和印防已毒素观察对刺激下丘脑诱发的升压反应的影响。结果：静脉注射安定和侧脑室注射氟安定均可抑制上述诱发的升压反应，侧脑室应用γ－氨基丁酸受体阻断剂印防已毒素可基本消除静脉注射安定对这种诱发升压反应的抑制作用。结论：安定对刺激下丘脑诱发的升压反应的抑制作用与γ－氨基丁酸受体激活有关
Objective: To investigate the effect of thalidomide on hypothalamic-induced vasorelaxation induced by diazepam. Methods: Rabbits with urethane and chloralose mixed intravenous anesthesia, phenol triiodide quaternary ammonium retardation, artificial respiration, intravenous stability, intraventricular injection of fluvastatin and printed toxins observed to stimulate the hypothalamic-induced l Impact of pressure response. Results: Intravenous injection of diazepam and intracerebroventricular injection of fluvastamine can inhibit the above-mentioned induced vasopressor response, and the application of γ-aminobutyric acid receptor blocker in the lateral ventricle can prevent the induced toxin The inhibitory effect of the reaction. Conclusion: The effect of diazepam on the hypotensive response induced by stimulation of hypothalamus is related to the activation of γ-aminobutyric acid receptor