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本文报道我院新生儿病区1988年10月至1993年10月住院的新生儿高胆红素血症(高胆)302例,并对这组病人进行分析,发现高胆发生率高,占同期新生儿病人的47.4%,其病因首位是G-6-PD缺陷症;其次是ABO溶血症;同时发现有丙酮酸激酶(PK)缺陷病;嘧啶5核苷酸酶(PS’N)缺陷病;和谷胱甘肽还原酶(GR)缺陷病。在本文新生儿高胆的病因分析中,各类酶缺陷病是影响新生儿高胆的重要因素。
This article reports 302 cases of neonatal hyperbilirubinemia (hypercholesterolemia) hospitalized in neonatal ward of our hospital from October 1988 to October 1993, and analyzed this group of patients and found that the incidence of high gallbladder, accounting for 47.4% of newborns in the same period, the cause of the first place is G-6-PD deficiency; followed by ABO hemolytic disease; also found pyruvate kinase (PK) deficiency; pyrimidine 5 nucleotidase (PS’N) defects Disease; and glutathione reductase (GR) deficiency disease. In this etiological analysis of neonatal hypercholesterolemia, various types of enzyme deficiency disease is an important factor affecting neonatal hypercholesterolemia.