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从柳叶忍冬95%乙醇提取物中首次分离并鉴定了20个化合物: ( +)-cycloolivil (1)、( +)-fraxiresinol (2)、prinsepiol(3)、软脂酸(4)、对甲基苯酚(5)、2,4-二羟基-3,6-二甲基苯甲酸甲酯(6)、洋芹素(7)、木犀草素(8)、5,7,4′-三羟基黄酮醇7-O-β-D-吡喃葡萄糖苷(9)、槲皮素(10)、染料木素(11)、5,4′-二羟基-7-甲氧基异黄酮(12)、染料木素5-O-β-D-吡喃葡萄糖苷(13)、5,4′-二羟基-7-甲氧基异黄酮5-O-β-D-吡喃葡萄糖苷(14)、5,7,4′-三羟基双氢黄酮7-O-β-D-吡喃葡萄糖苷(15)、丁二酸(16)、( +)-儿茶素(17)、( -)-表儿茶素(18)、谷甾醇(19)和胡萝卜苷(20).应用波谱方法及与已知品对照进行结构鉴定.其中,化合物10、17和18是抑制血管紧张素转化酶的活性成分.表4参63
20 compounds were first isolated and identified from the 95% ethanol extract of Lonicera japonica: (+)-cycloolivil (1), (+)-fraxiresinol (2), prinsepiol (3), palmitic acid (4), Methylphenol (5), methyl 2,4-dihydroxy-3,6-dimethylbenzoate (6), celery (7), luteolin (8), 5,7,4’- Trihydroxyflavonol 7-O-β-D-glucopyranoside (9), quercetin (10), genistein (11), 5,4′-dihydroxy-7-methoxyisoflavone ( 12) Genistein 5-O-β-D-glucopyranoside (13), 5,4′-dihydroxy-7-methoxyisoflavonoid 5-O-β-D-glucopyranoside ( 14) 5,7,4’-trihydroxydihydroflavone 7-O-β-D-glucopyranoside (15), succinic acid (16), (+)-catechin (17), ( -)-epi-catechin (18), sitosterol (19) and carotenoid (20). Spectroscopic methods were used for structural identification with known products. Among them, compounds 10, 17 and 18 inhibited angiotensin conversion. Enzyme active ingredients. Table 4 Reference 63