Synthesis of a Novel Series of S-Alkyl Thiobenzoate Compounds as Farnesyltransferase Inhibitors

来源 :中国化学快报(英文版) | 被引量 : 0次 | 上传用户:fooguo3007
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
S-akyl thiobenzoate compounds were designed as famesyltransferase (FTase) inhibitors.An effective synthetic method was explored. The structures of the target compounds were elucidated by NMR spectral and elemental analysis.
其他文献
The thermodynamic behavior of organic contaminants in soils is essential to develop remediation technologies and assess risk from alternative technologies. Ther
For improving the environmental quality and ensuring supply of wood and non-timber forest products, many forests have been planted in plain areas of China. Scie
A novel amphoteric granular lignin adsorbent(AGLA) was prepared using magnesium lignosulfonate as a raw material which was provided by a straw sulfite pulp mill
The TiO2 nanotube sample was prepared via a NaOH solution in a Teflon vessel at 150℃. The as-prepared nanotubes were then treated with H2 SO4 solutions. The Ti
Picea mongolica W. D. Xu. is an endemic species in China. The spruce forest is only found in semi-arid habitat in Inner Mongolia Autonomous Region of China. Bas
The degradation kinetics of strains P05 and P07 and the degradation effects of mixed strain on Microcystis aeruginosa were studied. The results showed that: ( 1
The neurotransmitter level changes of ducks exposed 8-month in a mercury-polluted site(Wanshan, China) and a reference site ( Shanghai, China) were examined. Ch
An innovative photoelectrode, B2O3·TiO2/Ti electrode, was prepared by galvanostaticanodisation. The morphology and crystalline examination results indicated th
A field experiment with a split-plot design was carried out at Dongbeiwang Farm in Beijing Municipality to establish reliable N fertilizer recommendation indice
Humic substrates are a major fraction of sediment organic matters, and the sorption of hydrophobic organic chemicals by humic substrates influences their behavi