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采用离体心做功模型，比较单低温（１０℃～１５℃）与低温加Ｓｔ．ＴｈｏｍａｓⅡ号心停搏液单剂与多剂灌注对未成熟兔全心缺血１２０分钟复灌６０分钟的作用。结果单剂组较单低温和多剂组心肌含水量，心肌线粒体丙二醛及心肌和冠脉流出液内皮素含量减少，冠脉流出液一氧化氮（ＮＯ）含量增加，微血管再开放良好，心肌细胞和内皮细胞超微结构损伤轻，最终心脏功能恢复优于其他二组；多剂组与单低温组差别不明显。提示低温加ＴｈｏｍａｓⅡ号液单剂灌注对未成熟兔心冠脉微循环及心功能保护作用优于单低温，多剂灌注无明显优点。
Using isolated heart function model, comparing single low temperature (10 ℃ ~ 15 ℃) with low temperature plus St.. Thomas Ⅱ heart cardioplegia single agent and multi-dose perfusion of immature rabbit immature rabbit 120 minutes reperfusion 60 minutes. Results Compared with the single-dose group, the myocardial water content, the content of myocardial mitochondrial malondialdehyde (MDA) and myocardial and coronary effluent decreased, the content of nitric oxide (NO) in coronary effluent increased, the reopened microvessel was better, Myocardial cells and endothelial cell ultrastructure damage light, the final cardiac function recovery is superior to the other two groups; multi-agent group and single hypothermia group difference was not obvious. Prompted low temperature plus Thomas Ⅱ single liquid perfusion on immature rabbit cardiac microcirculation and cardiac function better than single cold, multi-dose perfusion no obvious advantage.