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对广州地区132对(264例)不明原因不孕夫妇,进行血清抗精子抗体测定,采用精子凝集试验(Sperm-agglutination test,SAT)和精子制动试验(Spermimmobilization test,SIT)方法。精子凝集试验有两种,即试管玻片凝集试验(Tube-Slide agglutination test,TSAT)及明胶凝集试验(Gelatin agglutination test,GAT)。试验同时与正常孕妇,未婚少女各132例及兔抗人精子血清做阴性和阳性对照。SAT(TSAT和GAT)试验结果有3.30％(4/132)男性患者及7.58％(10/132)女性患者为阳性。SIT试验有3.30％(4/132)男性患者与6.81％(9/132)女性患者为阳性。试验结果提示:对不明原因不孕患者有必要先排除由抗精子抗体这一免疫因素所引起的不孕。
Serum anti-sperm antibodies were measured in 132 (264) infertile couples in Guangzhou using the Sperm-agglutination test (SAT) and Spermimmobilization test (SIT). There are two types of sperm agglutination test: Tube-Slide agglutination test (TSAT) and gelatin agglutination test (GAT). At the same time with the normal pregnant women, unmarried girls and 132 cases of rabbit anti-human sperm serum negative and positive control. SAT (TSAT and GAT) test results were 3.30% (4/132) of male patients and 7.58% (10/132) of female patients were positive. In the SIT trial, 3.30% (4/132) of males and 6.81% (9/132) of females were positive. Test results suggest that: It is necessary for patients with unexplained infertility to exclude infertility caused by the immune factor of anti-sperm antibody.