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目的探讨血清嗜酸性粒细胞阳离子蛋白(ECP)在咳嗽变异性哮喘(CVA)患儿中的检测方法和临床意义。方法对79例CVA患儿(哮喘组)和56例正常健康儿童(对照组)均进行血清ECP检测,并对其结果进行临床分析。结果血清ECP水平哮喘组明显高于对照组[(36.12±25.80)μg/L vs(7.62±4.90)μg/L,P<0.05]。结论 CVA与血清ECP水平密切相关,尽早对患儿进行血清ECP水平检测,有助于协助诊断,对早期预防干预CVA具有重要指导意义。
Objective To investigate the detection and clinical significance of serum eosinophil cationic protein (ECP) in children with cough variant asthma (CVA). Methods 79 cases of CVA children (asthma group) and 56 normal healthy children (control group) were detected by serum ECP, and the results of clinical analysis. Results Serum ECP levels in asthma group were significantly higher than those in control group [(36.12 ± 25.80) μg / L vs (7.62 ± 4.90) μg / L, P <0.05]. Conclusions CVA is closely related to the level of serum ECP. Early detection of serum ECP levels in children may be helpful in diagnosis. It is of great guiding significance for early prevention of CVA.