“阿及宁”即6-氨基嘌呤。在生物有机体的代谢中起着重要作用,它包含在核酸、核甙核酸及某些重要辅酶的组成中,近年来作为刺激白血球增生药物而应用于医学上。文献上合成“阿及宁”的路线实际上都有困难,如由尿酸经过6-氨基-2,8-二氯嘌呤而合成“阿及宁”必须在高压下进行;用三聚氢酸酯或氢来代替氢巯基的应应不顺利。本 “A and Ning” is 6-aminopurine. It plays an important role in the metabolism of biological organisms. It is contained in the composition of nucleic acids, nucleoside nucleic acids and some important coenzymes. In recent years, it has been used as a medicine for stimulating leukocyte proliferation in medicine. Literature in the synthesis of “A and Ning” route actually have difficulties, such as from uric acid through 6-amino-2,8-dichloropurine and the synthesis of “A and Ning” must be carried out under high pressure; with trimetarate Or hydrogen instead of hydrogen mercapto should not be smooth. this