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亚胺唑〔Miconazole,2,4二氯-β-(2,4二氯苯氧苯乙基)咪唑〕系一种广谱抗真菌制剂,在试管内对大多数病原性真菌、酵母菌及一些革兰氏阳性菌有效.某些研究已显示它外用治疗念珠菌病及皮癣菌病的疗效.至今可供选用的静注治疗广泛皮肤及系统性真菌感染的化疗制剂不多,仅有5-氟胞嘧啶、异乙硫氨基酪酸、羟基脒?及二性霉素乙等,其中5-氟胞嘧啶及羟基脒?的适应症有限,而二性霉素乙虽对真菌病有效,但其严重副作用限制了它
Miconazole, 2,4-dichloro-β- (2,4-dichlorophenoxy-phenethyl) imidazole, is a broad-spectrum antifungal agent that inhibits most pathogenic fungi, yeasts and yeasts in vitro Some Gram-positive bacteria are effective, and some studies have shown that it is topical for the treatment of candidiasis and dermatophytosis. The number of chemotherapy preparations available to date for the treatment of a wide range of skin and systemic fungal infections is small 5-fluorocytosine, isobutylthiacine, hydroxyamidine and amphotericin B, of which 5-fluorocytosine and hydroxylamidine? Indications are limited, while amphotericin B is effective against mycosis, But its serious side effects limit it