论文部分内容阅读
目的探讨分析骨科创面蜡样芽胞杆菌的感染情况,研究其耐药性及临床特点,为患者治疗提供参考依据。方法随机选取2011年6月-2013年6月收入的30例骨科创面蜡样芽胞杆菌感染患者作为观察组,同期选取30名健康人作为对照组,比较两组受试人员临床特点及耐药性,数据采用SPSS 19.0软件进行统计分析。结果观察组的30例患者中23例发生创面感染,感染率为76.7%;实验室检查结果显示,观察组患者的总蛋白含量为(49.94±8.24)g/L,低于对照组的(69.57±2.60)g/L,差异有统计学意义(P<0.05);观察组患者对亚胺培南、环丙沙星、万古霉素等抗菌药物的耐药率<15.0%,对青霉素G、头孢唑林等其他抗菌药物的耐药率较高,均>80.0%。结论蜡样芽胞杆菌感染患者常伴营养不良、免疫力低下,且发生开放性骨折、创面污染的患者易发生感染;应对症给予患者支持治疗,酌情补充白蛋白,依据药敏试验结果,择优选择抗菌药物进行治疗。
Objective To investigate the infection of Bacillus cereus in orthopedic wounds, study its drug resistance and clinical features, and provide a reference for the treatment of patients. Methods Thirty patients with the infection of Bacillus cereus in orthopedic wound were selected randomly from June 2011 to June 2013 as the observation group and 30 healthy persons were selected as the control group at the same time. The clinical characteristics and drug resistance of the two groups were compared The data were analyzed by SPSS 19.0 software. Results In the 30 patients in the observation group, wound infection occurred in 23 of 23 patients, the infection rate was 76.7%. The results of laboratory tests showed that the total protein content of the observation group was (49.94 ± 8.24) g / L, lower than that of the control group (69.57 ± 2.60) g / L, the difference was statistically significant (P <0.05). In the observation group, the resistance rate to antibacterials such as imipenem, ciprofloxacin and vancomycin was less than 15.0% Cefazolin and other antibacterials higher resistance rates, were> 80.0%. Conclusions Patients with Bacillus cereus infection often suffer from malnutrition and low immunity, and patients with open fractures and wound contamination are prone to infection. Patients should be treated with symptomatic treatment and albumin supplemented as appropriate. According to drug susceptibility test results, Antibacterial drugs for treatment.