目的观察孕免人轮状病毒（ＨＲＶ）血症是否会导致富内感染。方法在新西兰孕兔妊娠的不同阶段，经耳静脉注射入轮状病毒Ｗａ株，造成孕兔的病毒血症（血浓度为５×１０７／Ｌ），然后用ＲＴ／ＰＣＲ技术；检测出生仔兔肠道组织内ＨＲＶ抗原。结果在孕兔妊娠的早、中，晚期，ＨＲＶ都能通过血胎屏障进入宫内在仔兔肠道内定居。结论提示仔免存在ＲＶ宫内感染的可能性。这将为研究人类ＲＶ宫内感染提供依据。 Objective To observe if pregnancy-induced human rotavirus (HRV) hyperlipidemia can lead to fulminant infection. Methods In different stages of gestation pregnancy in New Zealand rabbits, the rotavirus Wa strain was injected through the ear vein to induce viremia in pregnant rabbits (blood concentration 5 × 107 / L) Intestinal tissue HRV antigen. Results In the early, middle and late pregnancy of pregnant rabbits, HRV could enter the intestine and settle in the intestine of rabbits through the blood-vessel barrier. Conclusions suggest that there is no possibility of RV intrauterine infection. This will provide the basis for the study of human RV intrauterine infection.