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大量资料表明,患有免疫抑制的实验动物和人群对病毒、真菌或细菌感染的易感性增强,肿瘤的发生率升高。据观察、啮齿类和人类在经常接触小剂量或无明显毒作用剂量的某些药物和化学物后,会引起免疫活性损害,这种损害可通过体液免疫和细胞免疫的降低反映出来。这些药物和化学物列于表1。癌作用的。但对此尚需寻找更多的直接证据。有些化学物和药物虽然没有免疫抑制的作用,却能引起速发型(如青霉素)或迟发型变态反应即过敏反应。例如,在清洁液、肥皂、
Numerous data indicate that experimental animals and populations with immunosuppression are more susceptible to viral, fungal or bacterial infections and have a higher incidence of tumors. It has been observed that regular exposure of rodents and humans to certain drugs and chemicals at low or no toxic doses causes damage to immunocompromised activity that is evidenced by reduced humoral and cellular immunity. These drugs and chemicals are listed in Table 1. The role of cancer. However, more direct evidence needs to be found. Some chemicals and drugs, although not immunosuppressive, can cause rapid onset (such as penicillin) or late-onset allergies, ie, anaphylaxis. For example, in the cleaning fluid, soap,