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蒲公英白屈菜水煎剂(TCD)能显著降低肠管蠕动频率和幅度,给药10min 降低肠管蠕动频率和幅度分别为对照组的56.6%和46.2%。二者与阿托品对照组比较作用明显,且维持时间较长。给药后20min降幅度作用为阿托品的43.1%两者比较差异显著(P<0.05)。实验结果还表明 TCD 对乙酰胆碱,组织胺引起的肠痉挛具有明显对抗作用。
Taraxacum celandine decoction (TCD) significantly reduced the frequency and amplitude of intestinal peristalsis, and administration of 10 min reduced the peristaltic frequency and amplitude of the intestinal tract by 56.6% and 46.2% of the control group, respectively. Both had a significant effect compared with the atropine control group and maintained longer. There was a significant difference between the two groups (43.1%) in which atropine was reduced by 20 minutes after administration, and the difference was significant (P<0.05). The experimental results also show that TCD has obvious antagonistic effects on acetylcholine and histamine-induced intestinal fistula.