论文部分内容阅读
近年来,血管扩张剂的临床应用日趋广泛,具有扩张血管作用的不同类型的药物亦不断增加,因而,扩血管剂对冠脉血流和心肌灌注的影响日益受到重视,特别在应用于心绞痛和心肌梗塞的患者。本文就正常和动脉粥样硬化时冠脉血流的调节、扩血管剂对冠脉血流的影响和临床应用的基本概念等加以讨论。一、正常冠脉血流的调节心外膜大的冠状动脉是“传输”血管,即使在显著扩张时,阻力亦仅有很小改变,一般
In recent years, the clinical application of vasodilators is becoming more widespread, and different types of drugs with dilated vasodilators are also increasing. Therefore, vasodilators have gained more and more attention on coronary blood flow and myocardial perfusion, especially in angina pectoris and Myocardial infarction patients. This article discusses the regulation of coronary blood flow during normal and atherosclerosis, the effects of vasodilators on coronary blood flow, and the basic concepts of clinical application. First, the regulation of normal coronary flow Large epicardial coronary artery is “transmission” of blood vessels, even in the significant expansion, the resistance has only a small change, the general