1991年2～4月我科先后接诊3例在外院婚前检查时被诊断为“尖锐湿疣”的男性患者,经检查均确诊为珍珠状阴茎丘疹病。患者均无自觉症状,临床表现为阴茎冠状沟处可见珍珠状,白色(2例)或红色(1例)半透明圆锥形丘疹,沿冠状沟排列成一行(2例)或数行(1例),丘疹互不融合,无压痛及破溃。病理检查:表皮正常,病变部位含有丰富的毛细血管网及纤维母细胞和密集的结缔组织,并有淋巴细胞浸润。醋酸湿敷试验均阴 From February to April 1991, our department admitted 3 male patients who were diagnosed as “condylomata acuminata” before the prenuptial examination in the outpatient department. All the patients were diagnosed as pearl pimple papulosis. Patients had no symptoms, the clinical manifestations of the penile coronary at the pearl, white (2 cases) or red (1 case) translucent conical papules, arranged along the coronary sulcus (2 cases) or a few lines (1 case ), Pimples are not fusion, no tenderness and ulceration. Pathological examination: normal epidermis, lesion site is rich in capillary network and fibroblasts and dense connective tissue, and lymphocyte infiltration. Acetic acid wet test are overcast