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目的:研究西比灵(IBL)辅助抗痫药(AEDs)在抗痫方面的临床价值。方法:将68例癫痫(EP)分为甲、乙两组。第一阶段甲组作为治疗组,乙组作为对照组。治疗组在对照组基础上加用西比灵胶囊,每日 10 mg,每晚一次,小儿按公斤体重给药,两组均用药3个月,然后评定其疗效。第二阶段乙组作为治疗组,第4个月开始,加用西比灵,用法同上,连用3个月,作同样观察,并以该组前3个月的观察结果用自身对照;同时还与连用6个月西比灵的甲组进行比较。结果:甲组(治疗组)加用西比灵后显效率与总有效率均明显优于对照组(P<0.01与P<0.05),甲组连用6个月西比灵,疗效进一步提高。西比灵对不同类型的EP均有效,而显效率有明显差别,特殊类型EP组优于全身大发作EP组(P<0.01)。结论:西比灵是一种安全有效抗EP的辅助新药,尤其对特殊类型EP更有应用前景。
Objective: To study the clinical value of anti-epilepsy drugs (IBSs) adjuvant antiepileptic drugs (AEDs). Methods: 68 cases of epilepsy (EP) were divided into A, B two groups. The first phase group A as the treatment group, the second group as the control group. The treatment group on the basis of the control group plus Sibelium capsules, 10 mg daily, once per night, pediatric weight-kilogram body weight, two groups were medication for 3 months, and then assess its efficacy. The second phase of Group B as a treatment group, the beginning of the 4th month, plus Xi Bailing, the same usage, used in conjunction for 3 months for the same observation, and the first 3 months of observation of the group with their own control; Compare with group A for 6 months xibeiling. Results: The effective rate and total effective rate of group A (treatment group) plus xibei Ling were significantly better than those of control group (group P <0.01 and group P <0.05). Group A was treated with xibei Ling for 6 months, The effect is further improved. Sibelium for different types of EP are effective, but the significant difference was markedly effective, special type EP group was better than the generalized EP group (P <0.01). Conclusion: Sibelium is a safe and effective anti-EP auxiliary new drug, especially for the special type of EP more application prospects.