中枢神经系统(CNS)中的小胶质细胞源于造血系统,是CNS的胶质细胞,又有着单核吞噬细胞的属性。在正常情况下,它对周围神经组织起着连续监视作用以维持CNS的稳态,小胶质细胞微小的异常也会引起机体的功能障碍;而当疾病或损伤发生时,失去了神经元的抑制作用,活化后的小胶质细胞作为CNS中的定植炎症细胞参与炎症反应与免疫应答。 Microglial cells in the central nervous system (CNS) are derived from the hematopoietic system and are CNS glial cells and have the properties of mononuclear phagocytes. Under normal circumstances, it plays a continuous surveillance of peripheral nerve tissue to maintain CNS homeostasis, microglia small abnormalities can also cause the body’s dysfunction; and when the disease or injury occurs, the loss of neurons Inhibition, activated microglia as inflammatory colonization in CNS cells involved in inflammatory response and immune response.