论文部分内容阅读
中科院武汉植物园在挖掘野葛根中催化异黄酮糖苷形成的糖基转移酶研究方面取得新进展,发现了两种相关基因的功用。该成果近日在线发表于《植物细胞报告》(Plant Cell Report)。糖苷是天然药物的修饰基团,能够增强小分子药物的水溶性与制剂成药的可操作性。野葛是一种豆科植物,其根富含多种异黄酮糖苷类化合物,具有降血脂、抗肿瘤,预防骨质疏松和女性更年期综合征等功效。所以,挖掘野葛根中催化异黄酮糖苷形成的糖基转移酶,对于新药合成与老
Wuhan Botanical Garden, Chinese Academy of Sciences in the excavation Pueraria catalytic isoflavone glycoside formation of glycosyltransferase research has made new progress and found the function of two related genes. The results recently published online in the “Plant Cell Report” (Plant Cell Report). Glycosides are natural drugs modified groups, can enhance the water-solubility of small molecule drugs and the feasibility of the preparation of drugs. Kudzu is a legume, the root is rich in a variety of isoflavone glycosides, with lipid-lowering, anti-tumor, prevention of osteoporosis and menopause syndrome and other effects. Therefore, the excavation of Pueraria catalyzed isoflavone glycoside formation of glycosyltransferase, for the synthesis of new drugs and old