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观察了100例试纸法尿蛋白阴性的糖尿病患者,采用放射免疫法联合检测β_2微球蛋白(β_2-M)、白蛋白(AIb)及IgG含量的变化。结果表明,糖尿病组AIb明显高于对照组(P<0.01),β_2-M及IgG均高于对照组(P<0.05)。我们认为,尿三项蛋白联合检测不仅能提高糖尿病肾病的早期检出率,而且有助于对损害部位及范围做出诊断。
100 cases of diabetic patients with urinary protein negative test strips were observed, and radioimmunoassay was used to detect the changes of β_2-MG, AIb and IgG. The results showed that AIb in diabetic group was significantly higher than that in control group (P <0.01), while β_2-M and IgG in control group were higher than those in control group (P <0.05). In our opinion, urinary tri-protein combined detection can not only improve the early detection rate of diabetic nephropathy, but also help to diagnose the location and extent of damage.