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一、研究心血管的放射性药物1.心血管(血池显象) 在核医学中放射性核素心血管造影已成为常规,这是一种研究巳知或疑似心脏病患者的诊断与评价的非创伤性试验。它可提供心脏全部和局部功能的定量指标。做这检查最早使用的显象剂是~(99m)Tc-人血清白蛋白。由于红血球的全身分布比白蛋白少,所以现在认为~(99m)Tc-标记自身红细胞是一种理想的显象剂。~(99m)Tc-红细胞常采用三种标记方法:体内、体外和体内与体外相结合。Pavel首先报道了体内标记红细胞并能得到较好标记率的方法。方法是受检者先注射非放射性锡-焦磷
Cardiovascular Radiopharmaceuticals 1. Cardiovascular (Blood Pool Imaging) Radionuclide cardiovascular imaging has become routine in nuclear medicine, a method of studying the diagnosis and evaluation of patients with known or suspected heart disease Traumatic test. It provides quantitative indicators of total and local cardiac function. The earliest developer to use for this test was ~ (99m) Tc-human serum albumin. Since whole body distribution of red blood cells is less than that of albumin, ~ (99m) Tc-labeled autologous red blood cells are now considered to be an ideal imaging agent. ~ (99m) Tc- erythrocytes often use three kinds of labeling methods: in vivo, in vitro and in vivo and in vitro binding. Pavel first reported on methods of labeling red blood cells in vivo and getting better labeling rates. The method is the first injection of non-radioactive tin - pyrophosphate