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目的:统计分析我院2013-2014年的药物不良反应(ADR)发生的特点及临床表现,为临床合理、安全用药提供参考。方法:对我院近两年上报的161例药物不良反应报告进行回顾性分析。结果:在上报的161份ADR报告中,男性ADR发生率略低于女性;引起ADR的主要给药途径为静脉滴注;引起ADR的药物中,以抗菌药物为最多见,其次是中成药;ADR的临床表现主要为皮肤及其附件损伤。结论:医院应继续加强ADR监测报告工作,提高医护药人员对ADR报告制度的认知。
Objective: To analyze the characteristics and clinical manifestations of adverse drug reaction (ADR) in our hospital from 2013 to 2014, and to provide a reference for clinical rational and safe drug use. Methods: A retrospective analysis of 161 reports of adverse drug reactions reported in our hospital in recent two years. Results: Among the 161 reported ADRs, the incidence of ADR in men was slightly lower than that in women. The main route of administration of ADR was intravenous drip. Of the ADR-causing drugs, antibacterials were the most common followed by proprietary Chinese medicines. The clinical manifestations of ADR mainly damage the skin and its accessories. Conclusion: The hospital should continue to strengthen the work of ADR monitoring and reporting to improve the cognition of medical staff on ADR reporting system.