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目的 :为进一步提高晚期乳腺癌的治疗效果 ,寻找有效的中西医结合治疗方法。方法 :乳腺癌治疗组采用 NVB加 DDP配合中药“生血汤”治疗晚期乳腺癌。结果 :总有效率 CR+PR为 52 % ,较 CMF、ACMF化疗方案疗效明显提高。本方案尤其对于乳腺癌锁骨上淋巴结转移或肺转移疗效较好 ,均各有 1例获得 CR,有效率分别为 75% ( 6/ 8)及 70 % ( 7/ 10 )。治疗中骨髓抑制等化疗副反应明显低于有关文献报道 ,其中白细胞下降率仅为 4 8% ,说明中药“生血汤”能明显减轻 NVB对骨髓造血功能的毒副作用 ,且能对化疗药物产生增效作用。结论 :NVB+DDP配合中药“生血汤”不失为目前治疗晚期乳腺癌较为理想的中西医结合方案
Objective: To further improve the treatment effect of advanced breast cancer, to find an effective combination of traditional Chinese and Western medicine treatment. Methods: Breast cancer treatment group using NVB plus DDP with traditional Chinese medicine “Sheng Xue Tang” treatment of advanced breast cancer. Results: The total effective rate of CR + PR was 52%, which was significantly higher than that of CMF and ACMF chemotherapy. The regimen has a good response to supraclavicular lymph node metastasis or lung metastasis of breast cancer. One case achieved CR, the effective rates were 75% (6/8) and 70% (7/10) respectively. Chemotherapeutic side effects such as myelosuppression were significantly lower than those reported in the literature, of which the leukopenia rate was only 48%, indicating that the Chinese medicine “Sheng Xue Tang” can significantly reduce the side effects of NVB on bone marrow hematopoietic function, and can increase chemotherapy drugs Effective effect. Conclusion: NVB + DDP combined with traditional Chinese medicine “Sheng Xue Tang” is an ideal combination of TCM and WM for the treatment of advanced breast cancer