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目的 探索正常人经肛门镜直肠粘膜下核素注射后 ,淋巴显像时间、正常淋巴引流图谱及直肠癌患者术前淋巴结转移的评估方法。 方法 1ml99m Tc右旋糖酐作为淋巴显像剂 ,对 3 7例正常人及 16例直肠癌患者经肛门镜直肠粘膜下注射 ,分别于注射后 1、2、3小时采用TOSHIBAGCA90 1A型SPECT机显像 ,获得正常人及直肠癌患者的核素淋巴引流闪烁图谱。 结果 在正常人直肠淋巴引流显像中均显示向头侧的淋巴引流链 ,3小时后平均显影的淋巴结为 12个。该方法用于直肠癌术前淋巴结转移的评估其敏感性为 97 1% ,特异性 75 0 % ,准确性 87 5 % ,假阳性率 2 5 0 % ,假阴性率8 3 %。 结论 该方法是一种较为理想的直肠癌淋巴转移的术前评估方法。
Objective To explore the method of assessing the lymph node metastasis of lymph node in patients with rectal cancer after anorectal mucosal radionuclide injection, lymph imaging time, normal lymph drainage patterns and rectal cancer patients. Methods 1 ml 99m Tc dextran was used as a lymphatic imaging agent. A total of 37 normal subjects and 16 rectal cancer patients underwent anorectal submucosal injection and were respectively subjected to TOSHIBAGCA90 1A SPECT machine imaging 1, 2 and 3 hours after injection. Nuclide lymphatic drainage scintigraphy in normal and rectal cancer patients. Results In normal human rectal lymphatic drainage imaging showed the first side of the drainage chain of lymph nodes, 3 hours after the average number of developed lymph nodes 12. The sensitivity and specificity of this method for the assessment of preoperative lymph node metastasis in patients with rectal cancer were 97.1%, 75.0%, 87.5% respectively, false positive rate 25.0% and false negative rate 83%. Conclusion This method is an ideal preoperative assessment of lymphatic metastasis of rectal cancer.