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孤立性直肠溃疡综合征(solitary rectal ulcer syndrome简称SRUS)常有粘液血便和过度用力排便史。溃疡位于直肠前壁,距肛缘6～10cm。正常情况下,排便时耻骨直肠肌处于抑制状态,而一部分SRUS患者则出现肌肉活动频率和幅度增加的反常运动。为了解过度用力排便与耻骨直肠肌反常运动所起的作用,作者用电生理的方法研究了骨盆底肌肉结构及其神经分布。 20例患者中,18例为女性,平均年龄36岁±12(20～70岁)。SRUS均经乙状结肠镜检查和活检确诊。平均发病时间5年,过度用力排便史平均17.3年,7例(35%)有完全性直肠脱垂,12例女性(60%)为经产
Solitary rectal ulcer syndrome (SRUS) often have mucus bloody stool and excessive force defecation. Ulcer located in the anterior rectal wall, from anal verge 6 ~ 10cm. Normally, puborectalis is inhibited during defecation, and some patients with SRUS experience an abnormal movement with increased frequency and amplitude of muscle activity. To understand the role of excessive forced defecation and abnormal puborectalis muscle movement, the authors used electrophysiological methods to study the structure of the pelvic floor muscle and its neural distribution. Of the 20 patients, 18 were female and average age was 36 ± 12 (20-70 years). SRUS confirmed by sigmoidoscopy and biopsy. The mean onset time was 5 years. The history of excessive forced defecation was 17.3 years. Complete rectal prolapse was found in 7 cases (35%) and in 12 women (60%).