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柳叶破布木Cordia salicifolia Cham. 系南美巴拉圭使用的具有滋补及利尿功能的传统药。在筛选对单纯疱疹I型病毒(HSV-I)具有抑制作用的植物过程中,发现它活性较强。本文介绍了此植物部分纯化的提取物COlI-6的药理研究,其制备过程如下: 干燥碾碎的枝叶用70％沸乙醇提取,减压浓缩后以氯仿/水萃取。氯仿部分减压浓缩得深棕色膏,然后在硅胶柱上以氯仿洗脱,得深绿色粉末,再经薄层纯化,得到在硅胶板上显示单点的深绿色粉末状物,即为(COLI-6,备用。
Cordia salicifolia Cham. is a traditional medicine with nourishing and diuretic functions used in Paraguay in South America. It was found to be highly active in the screening of plants that have inhibitory effects on herpes simplex virus type 1 (HSV-I). This article describes the pharmacological study of the partially purified extract of this plant, COII-6. The preparation process is as follows: The dried crushed leaves are extracted with 70% boiling ethanol, concentrated under reduced pressure and extracted with chloroform/water. The chloroform portion was concentrated under reduced pressure to give a dark brown paste, which was then eluted with chloroform on a silica gel column to give a dark green powder, which was then purified in a thin layer to give a dark green powder that showed a single spot on the silica gel plate. -6, spare.