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对系统抗结核治疗了1月~3月无明显好转的6例Ⅲ期结核性脑膜脑炎病人予异烟肼50mg、地塞米松1.5mg、链霉素0.1g生理盐水稀释后鞘内缓慢注射,10次为一疗程,脑脊液恢复正常1周以上停药继续用抗结核药治疗,随访1年~2年。结果:鞘内注药后病情均显著好转,1个疗程后脑脊液恢复正常,复发后继续用效果仍好。鞘内用药未见严重毒副作用。结论:鞘内注药治疗重症结核性脑膜炎疗效显著。
6 cases of stage III tuberculous meningoencephalitis who had no significant improvement in anti-TB treatment from January to March were treated with isoniazid 50 mg, dexamethasone 1.5 mg and streptomycin 0.1 g diluted with saline Slow injection, 10 times for a course of treatment, normal cerebrospinal fluid returned to normal for more than 1 week to continue treatment with anti-TB drugs, followed up for 1 year to 2 years. Results: After intrathecal injection, the condition was significantly improved. After one course of treatment, cerebrospinal fluid returned to normal, and the effect was still good after recurrence. Intrathecal medication without serious side effects. Conclusion: Intrathecal injection of severe tuberculous meningitis has a significant effect.