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目的研究男男性行为人群(MSM)感染艾滋病病毒(HIV)的危险因素及其交互作用,为艾滋病干预提供科学依据。方法 2013年7月至2014年2月,在深圳市慢性病防治中心MSM项目门诊和夕颜文化传播中心MSM关爱室,招募MSM进行一对一的问卷调查,并采集5~10mL外周静脉血检测HIV和梅毒抗体。以HIV感染状况为因变量,人口学特征、艾滋病知识知晓情况、梅毒感染状况、性行为状况等为自变量,进行单因素和多因素非条件Logistic回归分析,在此基础上进行交互作用分析。结果共调查406名MSM,完成调查的369名MSM,有效率90.9%。低文化程度、梅毒感染、自认感染风险低、正确用安全套能否预防HIV(安全套预防认知)、肛交角色为被动方,是MSM发生HIV感染的危险因素,梅毒与学历之间、固定性伴与网络寻找性伴之间、肛交角色与肛交用套之间存在交互作用,性取向分别与居住状态、梅毒、性病史之间存在交互作用。结论 MSM的HIV感染是多种危险因素引起的,各危险因素之间的交互作用更提示MSM艾滋病防治的复杂性,对其干预应采取综合措施。
Objective To study the risk factors and interactions of HIV infection among men who have sex with men (MSM) and provide a scientific basis for AIDS intervention. Methods From July 2013 to February 2014, one-on-one questionnaires were recruited from MSM project clinic of Shenzhen Chronic Disease Prevention and Control Center and MSM Care Center of Xianyan Culture Communication Center to collect MSM from 5 to 10 mL peripheral venous blood to detect HIV And syphilis antibody. The HIV infection status as a dependent variable, demographic characteristics, AIDS knowledge, syphilis infection status, sexual behavior as independent variables, univariate and multivariate non-conditional Logistic regression analysis, based on the interaction analysis. Results A total of 406 MSMs were surveyed and 369 MSM completed the survey, with an effective rate of 90.9%. Low level of education, syphilis infection, low risk of infection, correct use of condoms to prevent HIV (condom prevention and cognition), and passive role in anal intercourse are the risk factors of MSM HIV infection, syphilis and education, fixed There is interaction between partner and network searching partner, anal intercourse and anal intercourse, sexual orientation and living status, syphilis and venereal disease. Conclusions HIV infection in MSM is caused by a variety of risk factors. The interaction between risk factors suggests the complexity of AIDS prevention and treatment of MSM. Comprehensive measures should be taken for its intervention.