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目的:观察康复新液与蒙脱石散治疗新生儿应激性溃疡出血的疗效。方法:将51例应激性溃疡出血的患儿随机分成治疗组26例和对照组25例,两组均予治疗原发病,西咪替丁抑制胃酸,静脉滴注酚磺乙胺止血,治疗组管饲康复新液与蒙脱石散,对照组管饲凝血酶,观察两组临床疗效及不良反应。结果:治疗组总有效率为92.3%,止血时间为(2.00±0.33)d,对照组总有效率为68.0%,止血时间为(3.00±0.68)d,两组比较差异均有统计学意义(χ2=4.5,P<0.05及t=6.621,P<0.01),两组均未发现明显不良反应。结论:康复新液与蒙脱石散管饲治疗新生儿应激性溃疡出血能提高总有效率并缩短止血时间,且简单、价廉,未见明显不良反应,值得临床推广。
Objective: To observe the curative effects of Kangfuxin and Montmorillonite in the treatment of neonatal stress ulcer hemorrhage. Methods: Totally 51 children with stress ulcer bleeding were randomly divided into treatment group (n = 26) and control group (n = 25). Both groups were given primary treatment, cimetidine inhibited gastric acid, The treatment group was given a new tube of fluconazole and montmorillonite powder, and the control group was fed with thrombin. The clinical efficacy and adverse reactions of the two groups were observed. Results: The total effective rate of treatment group was 92.3%, the bleeding time was (2.00 ± 0.33) d, the control group was 68.0%, the bleeding time was (3.00 ± 0.68) d, the differences were statistically significant χ2 = 4.5, P <0.05 and t = 6.621, P <0.01). No significant adverse reactions were found in both groups. CONCLUSION: Kangfuxin liquid and montmorillonite bulk tube feeding can improve the total effective rate and shorten the time of hemostasis in the treatment of stress ulcer hemorrhage. It is simple, inexpensive and has no obvious adverse reactions, which is worthy of clinical promotion.