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苯二氮受体被反激动剂占领后诱发焦虑的机理不明。本文用国产大鼠操作性条件反射仪和电击行为冲突程序,首次观察到去甲肾上腺素和内啡肽递质共同参与苯二氮(艹卓)受体反激动剂DMCM的致焦虑作用。 电击行为冲突程序核实验要求可予置若干单元。每一中元由无冲突期和冲突期组成。两期的时间予置在训练和强化阶段分别为5min和3min。实验日则分别为5min和10min。两期中操作程序分别固定为FR_4和
The mechanism by which benzodiazepine receptors are induced by inverse agonists to induce anxiety is unknown. This article for the first time observed that norepinephrine and endorphin transmitters participate in the anxiety-inducing action of the benzodiazepine agonist DMCM. Shock behavior Conflict Procedure Nuclear test requirements can be set to a number of units. Each yuan consists of no conflict and conflict. Two periods of time set in the training and strengthening phase were 5min and 3min. Experimental days were 5min and 10min. The two operating procedures were fixed as FR_4 and