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1937年Kuroda第一次报道了日本一钢铁厂中炼焦部分煤气厂工人肺癌的流行病学调查,在1931～1935期间共有61例恶性肿瘤死亡,而其中肺癌为12例,全系煤气厂工人。煤气分厂工人肿瘤的比例为:肺癌80％(12/15)胃癌13％(2/15),肝癌7％(1/15)。而其它各分厂工人的肿瘤比例为肺癌0％,胃癌65％(30/46),肝癌24％(11/46),其它癌为11％(5/46)。煤气分厂的肺癌工人的平均接触年限为16.6年。22867名工人中,5年发病粗率的计算结果,肿瘤为2.67‰,肺癌为0.53‰。
In 1937 Kuroda reported for the first time an epidemiological investigation of lung cancer in some coal-fired power plant workers in a steel plant in Japan. Between 1931 and 1935, a total of 61 deaths from malignant tumors were reported, of which 12 were lung cancer and were all coal-gas workers. Gas factory workers in the proportion of tumors: lung cancer 80% (12/15) 13% of gastric cancer (2/15), liver cancer 7% (1/15). The proportion of tumor in other branch factories was 0% in lung cancer, 65% (30/46) in gastric cancer, 24% (11/46) in liver cancer, and 11% (5/46) in other cancers. The average life span of lung cancer workers in gas plants is 16.6 years. 22867 workers, 5-year incidence of crude calculations, the tumor was 2.67 ‰, lung cancer was 0.53 ‰.