作者在讨论妊娠期间利尿剂的应用问题时指出:我们同意血压正常时,利尿剂对水肿有良好的效果,很决不同意妊娠中毒症时不恰当地使用利尿剂。众所周知,先兆子痫与低血容量有关。而应用噻嗪类利尿剂将更加减少血容量。Gant等氏于研究九名孕妇应用噻嗪类治疗第七天时,发现去氢椎甾酮硫酸钠盐代谢产物的清 In discussing the use of diuretics during pregnancy, the authors point out that we agree that diuretics have a good effect on edema when blood pressure is normal, and we strongly disagree with inappropriate use of diuretics during gestational toxicities. It is well-known that preeclampsia is associated with hypovolemia. The use of thiazide diuretics will be more to reduce blood volume. Gant et al in the study of nine pregnant women on the seventh day of treatment with thiazide, found that anti-pinostatin sodium sulfate salt metabolites