论文部分内容阅读
目的 研究外周微循环白色微血栓和血液流变学变化与肾病综合征 (NS)并肾静脉血栓形成(RVT)之间的关系。方法 采用螺旋CT肾静脉连续薄层增强扫描 ,将 10 0例NS患儿分为Ⅰ组 (无RVT ,88例 )和Ⅱ组 (合并RVT ,12例 )。甲皱微循环下观察白色微血栓。血液流变学指标检测按常规方法 ,包括全血比粘度、血浆比粘度、红细胞电泳、血细胞压积。结果 1.Ⅱ组白色微血栓阳性率明显高于Ⅰ组 (P <0 .0 1)。 2 .Ⅰ组、Ⅱ组全血比粘度 (高切、低切 )、红细胞电泳时间、血细胞压积均显著高于对照组 (P <0 .0 0 1,P <0 .0 1) ;Ⅱ组全血比粘度 (高切、低切 )、红细胞电泳时间显著高于Ⅰ组 (P <0 .0 0 1)。Ⅰ、Ⅱ组血细胞压积无显著性差异 (P>0 .0 5 )。Ⅰ、Ⅱ组、对照组血浆比粘度无显著性差异 (P >0 .0 5 )。结论 NS患儿外周微循环白色微血栓阳性和血液流变学变化与RVT之间有密切关系
Objective To study the relationship between peripheral microcirculation micro-thrombus and hemorheological changes and nephrotic syndrome (NS) and renal vein thrombosis (RVT). Methods One hundred and ten patients with NS were divided into group Ⅰ (without RVT, 88 cases) and group Ⅱ (with RVT, 12 cases) by continuous spiral CT renal vein thin layer scanning. A small white blood clots observed under microcirculation. Hemorheology index detection by conventional methods, including whole blood specific viscosity, plasma viscosity, erythrocyte electrophoresis, hematocrit. Results 1. The positive rate of white microthrombi in groupⅡwas significantly higher than that in groupⅠ (P0.01). The whole blood specific viscosity (high and low cut), erythrocyte electrophoresis time and hematocrit in group I and group II were significantly higher than those in control group (P <0.01, P <0.01) Group of whole blood specific viscosity (high-cut, low-cut), erythrocyte electrophoresis time was significantly higher than the group Ⅰ (P <0. There was no significant difference in hematocrit between group Ⅰ and group Ⅱ (P> 0.05). There was no significant difference in plasma specific viscosity between group Ⅰ, Ⅱ and control (P> 0.05). Conclusion The positive rate of micro-thrombosis in peripheral microcirculation and the change of hemorheology in NS children are closely related to RVT