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目的通过与阿莫西林克拉维酸钾的前瞻对照性研究,观察头孢妥仑匹酯在治疗泌尿系感染中的药效及安全性。方法选择80例确诊为泌尿系感染患者分两组,每组40例,两组年龄、性别及病程无显著性差异。分别给予头孢妥仑匹酯200mg,口服和阿莫西林克拉维酸钾375mg,疗程均为7～14d。结果两种抗生素对泌尿系感染的疗效都较满意,而两组之间在药效及安全性方面则无显著差异。结论头孢妥仑匹酯在治疗泌尿系感染中疗效肯定且安全性好。
Objective To observe the efficacy and safety of cefditoren pivoxil in the treatment of urinary tract infection by prospective controlled study with potassium of amoxicillin and clavulanate. Methods Eighty patients diagnosed as urinary tract infection were divided into two groups, 40 cases in each group. There was no significant difference in age, sex and course of disease among the two groups. They were given cefditoren diclofenac 200mg orally and amoxicillin and clavulanate 375mg, the course of treatment was 7 ~ 14d. Results Both antibiotics were more satisfactory for the treatment of urinary tract infection, while there was no significant difference in efficacy and safety between the two groups. Conclusions Cefditoren pivoxil is effective and safe in the treatment of urinary tract infection.