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用Beekman121MB氨基酸分析仪测定小鼠全脑GABA含量:梭曼中毒惊厥时脑内GABA含量没有变化,致惊药异烟肼中毒时含量明显下降;安定、4—氨基丁酸和阿托品腹腔预防注射对梭曼中毒小鼠有一定的抗惊厥作用,但并不影响其脑内GABA的含量。
The content of GABA in the whole brain of mice was determined by Beekman121MB amino acid analyzer: the contents of GABA in the brain did not change after soman poisoning convulsion, and the content of GABA was significantly decreased when the drug was induced by isoniazid instillation; diazepam, 4-aminobutyric acid and atropine intraperitoneal injection Soman poisoning mice have a certain anticonvulsant effect, but does not affect the brain GABA content.