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细菌耐药性可分为天然(或原发)耐药性及获得耐药性两种,前者一般不会改变。本文系指获得耐药性而言。一、细菌耐药性产生的类型(一)突变细菌可经X射线、紫外线、氮芥或环氧化合物等物理或化学因素处理而诱发突变;突变也可为遗传因子(基因)DNA自发变化的结果。耐药性多由后一种情况形成。每一基因有一极低的突变率,当细菌细胞分裂10~5～10~9代后才出现一次对某种抗生素的耐药现象,即每10~5～10~9个细菌中可有一只细菌对此抗生
Bacterial drug resistance can be divided into natural (or primary) drug resistance and access to two kinds of resistance, the former generally do not change. This article refers to the acquisition of resistance in terms of. First, the type of bacterial resistance (A) Mutant bacteria can be X-ray, UV, nitrogen mustard or epoxy compounds and other physical or chemical treatment induced mutation; mutation can also genetic (gene) DNA spontaneous changes result. The latter is mostly the result of the latter. Each gene has a very low mutation rate, when the bacterial cells after 10 to 5 to 10 to 9 generations of the emergence of a resistance to antibiotics, that is, every 10 to 5 to 10 to 9 bacteria can have one Bacteria antibiotics