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应用免疫组化ABC法对165例非何杰金淋巴瘤(NHL)与低分化和未分化癌进行了角蛋白(ke),上皮膜抗原(EMA),癌胚抗原(CEA)和白细胞共同抗原(LCA)标记,165例标本中组织化学确诊为癌的有41例,NHL34例,免疫组化结果与组织学诊断一致;NHL与低分化和未分化癌需要鉴别的90例,其中常规组织学未能确诊的有72例,有争议的6例,这78例标记后明确了诊断,另外12例原组织学为误诊,已由免疫组化纠正。结果表明,应用免疫组化技术对NHL与低分化和未分化癌的鉴别诊断有实用价值。
Immunohistochemical ABC method was used to analyze keratofe (ke), epithelial membrane antigen (EMA), carcinoembryonic antigen (CEA) and leukocyte common antigen in 165 non-Hodgkin’s lymphoma (NHL) and poorly differentiated and undifferentiated carcinomas. (LCA) markers, 165 histological specimens were histologically confirmed as having cancer in 41 cases, NHL 34 cases, immunohistochemistry results were consistent with histological diagnosis; NHL and poorly differentiated and undifferentiated carcinomas need to be identified in 90 cases, among them conventional histology Of the 72 cases that failed to be diagnosed, 6 cases were controversial. The 78 cases were clearly diagnosed after labeling. The other 12 cases were misdiagnosed with original histology and had been corrected by immunohistochemistry. The results showed that the application of immunohistochemistry has practical value in the differential diagnosis of NHL and poorly differentiated and undifferentiated cancers.