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目的探讨胎儿血管炎(FV)与新生儿呼吸窘迫综合征(RDS)发生的关系。方法回顾性分析2009年10月至2013年6月在我院新生儿科住院的胎龄28~32周早产儿,纳入绒毛膜羊膜炎与FV结果一致的病例,并根据是否合并FV分为FV阳性组及FV阴性组,比较两组早产儿RDS发生率及分级情况。结果收治符合标准的早产儿共266例,组织学绒毛膜羊膜炎阴性、FV阴性组202例,RDS发生率67.3%;组织学绒毛膜羊膜炎阳性、FV阳性组64例,RDS发生率42.2%,FV阳性组早产儿RDS发生率低于FV阴性组,差异有统计学意义(P<0.05),两组早产儿RDS程度差异无统计学意义(P>0.05)。结论 FV可以减少早产儿RDS发生率,但对RDS程度影响不明显。
Objective To investigate the relationship between fetal vasculitis (FV) and neonatal respiratory distress syndrome (RDS). Methods A retrospective analysis of 28-32 weeks gestational age preterm infants hospitalized in neonates of our hospital from October 2009 to June 2013 was included in the cases of chorioamnionitis and FV. According to whether the FV was positive or not, Group and FV negative group. The incidence and classification of RDS in the two groups were compared. Results A total of 266 premature infants were eligible. Histology was negative in chorionic amniocentesis, 202 cases were in FV negative group, the incidence of RDS was 67.3%. The histological chorioamnionitis was positive in 64 cases of FV positive group, the incidence of RDS was 42.2% The incidence of RDS in preterm infants with FV positive group was lower than that in FV negative group, the difference was statistically significant (P <0.05). There was no significant difference in RDS between the two groups (P> 0.05). Conclusion FV can reduce the incidence of RDS in preterm infants, but has no obvious effect on the degree of RDS.