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采用高分辨率B型超声显象法检测94例不同血清胆固醇水平的老年人的颈动脉内膜和中膜厚度,旨在探讨老年人的颈动脉内膜和中膜厚度与冠心病及高胆固醇血症等心血管病危险因素的关系。结果发现,不同胆因醇水平的三组间内膜和中膜厚度差异无显著性,但颈动脉内膜和中膜厚度与年龄、收缩压、总胆固醇和低密度脂蛋白胆固醇水平有显著的正相关性。内膜和中膜厚度增加者(≥1.0mm)吸烟、高血压病、冠心病及脑梗塞的发生率明显高于内股和中膜厚度正常者(<1.0mm)。Logistic多因素回归分析发现年龄是内膜和中膜厚度增加的独立影响因素。因此,多种因素不同程度地影响老年人的颈动脉内膜和中膜厚度.颈动脉内膜和中膜厚度作为一种无创性检查指标可用于观察老年人动脉粥样硬化的变化情况。
The carotid intima and media thickness were measured in 94 elderly people with different serum cholesterol levels by high resolution B-mode ultrasound. The aim was to investigate the relationship between carotid intima-media thickness and coronary heart disease and high cholesterol Relationship between blood pressure and other cardiovascular risk factors. The results showed that there was no significant difference in the thickness of intima and media between the three groups with different levels of biliary alcohol, but there were significant differences in carotid intima and media thickness and age, systolic blood pressure, total cholesterol and low density lipoprotein cholesterol Positive correlation. The incidence of smoking, hypertension, coronary heart disease and cerebral infarction in patients with increased intima and media thickness (≥1.0 mm) was significantly higher than those with normal intima and media thickness (<1.0 mm). Logistic multivariate regression analysis showed that age was an independent factor in the increase of intima and media thickness. Therefore, a variety of factors affect the degree of carotid intima-media thickness in the elderly to varying degrees. Carotid intima and media thickness as a noninvasive test indicators can be used to observe changes in the elderly atherosclerosis.